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Dawn, a California teen who has run away to New York, tries to contact her foster mother Louise, a Red Cross doctor in Pakistan, following the terrorist attacks of September 11, 2001, and instead reaches Louise's assistant, Johar, a refugee from Afghanistan, and the two form a bond that gives them both hope and courage to face the future.

The author relates his experiences speaking and traveling with an African refugee named Deo, who escaped genocide and earned his doctorate degree in medicine from Columbia Universtity, to Burundi, where Deo built a hospital and reflected on the many deaths in the region.

When ten-year-old Drita and her family, refugees from Kosovo, move to New York, Drita is teased about not speaking English well, but after a popular student named Maxine is forced to learn about Kosovo as a punishment for teasing Drita, the two girls soon bond.

When she was twelve, Prenna James emigrated to New York City from the future.

After having escaped with his family from Nazi-occupied France, Gustave finds a home in New York City, still worried about Marcel, his good friend who he left behind, and surprised to find bigotry in America, too.