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Mandy and James try to find someone to care for a mare whose owner has left the country.

When Mandy's dad diagnoses an Old English sheepdog puppy as deaf, Mandy feels sorry for it.

At Animal Ark, Mandy Hope helps her parents treat animals of all shapes and sizes.

Mandy and James try to help twin foals that are sick while attempting to keep Drysdale Farm from financial ruin.

One night, Mandy finds a distressed golden retriever tied up outside Animal Ark-- with no sign of her owner.

Mandy tries to help a dolphin in an animal park after the dolphin's partner dies.

Mandy and James are sad that their friend Wilfred Bennett has to sell his riding stables.

Mandy Hope, accustomed to helping out at the Animal Ark veterinary clinic, faces a real challenge when Tania Benster, a new girl upset over the recent divorce of her parents, refuses to care for the miniature horse that was meant to be her birthday present.

Mandy and James visit London where they try to rescue a lost puppy from the dangers of the big city.

Mandy is convinced that she wants to be a vet when she grows up. Her parents arrange for her to visit a London animal hospital and work with an SPCA inspector for a week.

Maggie MacKenzie is grounded by her grandmother until her grades improve, but when sick and dying puppies begin pouring into the clinic, Maggie sets out to find the puppy mill responsible.

Mandy, haunted by dreams of a strange, stone-colored cat, wonders of the mysterious feline is trying to give her clues about a missing tabby cat, Bathsheba.

While helping to set up a Santaland outside Walton Cottage Hospital, Mandy and James spot a stray Jack Russell terrier, and hatch a plan to match the puppy with Charlie, a young patient they have befriended who desperately wants a dog for Christmas.

Mandy and James visit a wildlife park in Scotland where they become involved in a quest to save two young resident wolves some locals want to have sent away.

During the school holiday performance Honey the hamster escapes from her cage and was last seen scurrying out into the snow under a holly bush; and now Mandy and James must find her before she freezes to death.